Program

09:00-09:30

Opening Ceremony

09:30-10:30

Keynote Lecture

Chair: Gail Gasparich

Jose Vazquez-Boland

 ‘Phylogenomics and prokaryotic genus demarcation’

10:30-11:00

Coffee Break

11:00-13:00

Seminar 1 – Genome Engineering and Synthetic Biology

Chairs: Glenn Browning & Laure Beven

11:00

Emmy Klieneberger-Nobel Award Lecture

Prof John I. Glass

‘Building and using synthetic mycoplasma cells to understand the first principle of cellular life’

11:50

John W. Sanford

48 - Protein moonlighting and sugar phosphate glycosylation retained in Mycoplasma genitalium and JCVI-syn3A

12:04

Jitra-Marie Jittasevi

86 - Compatibility defects in the protein content of donor and recipient genomes may lead to genome transplantation failure

12:18

Maurici Trasserra-Teixido

110 - Single-Shot xCas9 system for seamless genome engineering in Mycoplasma genitalium

12:32

Carole Lartigue

112 - Establishing whole genome transplantation in major pathogen species Mycoplasma bovis

12:46

Lucas Miranda Marques

134 - Genome-reduced synthetic Mycoplasma mycoides strains differentially modulate innate and adaptive immunity in goats

13:00-14:00

Lunch Break

14:00-16:00

Symposium 1 – Virulence and Pathogenesis of Mycoplasmas

Chairs: Eric Baranowski & Rohini Chopra-Dewasthaly

14:00

Jiayi Wang

16 - Fructose-1,6-bisphosphate aldolase inhibits Mycoplasma bovis growth by upregulating cell division protein FtsZ

14:15

Menghui Liu

24 - Mycoplasma mycoides subsp. mycoides nucleomodulin Ts0703 promotes macrophage pyroptosis through SOD2-dependent oxidative stress

14:30

Yonathan Arfi

37 - An atypical F-type ATPase is necessary for the function of the antibody cleavage system MIB-MIP in mycoplasmas

14:45

Guanhua Xue

45 - Characterizing the nuclease activity of Mpn133: implications for host cell apoptosis and immune evasion in Mycoplasma pneumoniae

15:00

Dilhani Ekanayake

49 - Characterising the role of the virulence associated gene F9C22_02975 as a pantothenate binding protein in Mycoplasma gallisepticum

15:15

Xing Xie

52 - Circulating L-Asparagine dictates mycoplasma susceptibility and drives nutritional virulence across species

15:30

Urszula Magdalena Oko

53 - Investigation of Mycoplasma genitalium antigens using targeted recombinant analysis and PhIP-Seq profiling

15:45

Nadeeka K. Wawegama

76 - Temporal changes in Mycoplasma bovis variable surface lipoprotein (vsp) gene transcription shape host immune responses in infected mammary glands

16:00

Short Talks 1

Chairs: Marco Bottinelli & Veronica Jarocki

Anne Boissiere

80 - Multi-approach exploration of Mycoplasma capricolum subsp. capripneumoniae exoproteome

Zhixin Feng

51 - Eradication strategies design for Mycoplasma hyopneumoniae from pig herds and Implementation in China

Calvin Ko

88 - Development of a rapid flow cytometry-based antimicrobial susceptibility test for Mycoplasma hyopneumoniae

Ana Fiorella Castillo Espinoza

93 - 3D Organotypic tracheal model reveals Mycoplasma hyopneumoniae-induced epithelial damage beyond bacterial culture status

Arlind Mara

104 - Dissecting the lesion-defined dynamics of host responses in contagious bovine pleuropneumonia

Robert Kammerer

118 - Host response to Mycoplasma mycoides subsp. mycoides upon experimental infection of European cattle

Lucy Duncombe

129 - Detecting exposure to Mycoplasma mycoides subsp. mycoides in ruminants using the ID Screen® CBPP competition ELISA kit

16:30-17:00

Coffee Break

17:00-18:00

Poster Session 1 (Odd number Abstracts)

18:00 -19:00

IRPCM meetings (Simultaneous)

Human Mycoplasmas

Avian Mycoplasmas

New and Emerging species

9:00

Keynote Lecture

Chair: Sabine Pereyre

Gilbert Greub

‘Chlamydia: from basic science to medical challenges’

10:00-13:00

Seminar 2 – Diagnostics and Epidemiology

Charis: Nadeeka Wawegama & Miklos Gyuranecz

10:00

Maureen Diaz

59 - Genomic epidemiology of Mycoplasma pneumoniae: Comparative analysis of global and recent united states trends

10:15

Sabine Pereyre

39 - Spread of multidrug-resistant and territory-specific Mycoplasma genitalium clones in France

10:30-11:00

Coffee Break

11:00

Peter Hannan Award Lecture

Joachim Spergser

‘Diversity of mycoplasmas in the animal host’

11:50

Ana Y. Morales-Arce

65 - Evolutionary diversification and population structure of Mycoplasma synoviae inferred from MLST data

12:04

Inna Lysnyansky

73 - National implementation of MS-H vaccination in broiler breeders reshapes Mycoplasma synoviae epidemiology in Israel: Six-year experience

12:18

Chloé Ambroset

102 - Two Mycoplasma species, two evolutionary trajectories: M. agalactiae and M. feriruminatoris in Alpine Ibex

12:32

Guoqing Shao

115 - A self-supervised learning approach for robust pig cough detection to support mycoplasmosis control of swine

12:46

Christiaan ter veen

116 - Quantification of the efficacy of Mycoplasma gallisepticum monitoring programmes to minimize vertical transmission.

13:00-14:00

Lunch Break

14:00-15:45

Symposium 2 – Virulence and Pathogenesis of Human Mycoplasmas

Chairs: Lucas Miranda Marques & Christine Citi

14:00

Marina Marcos-Silva

14 - Sources of essential lipids for Mycoplasma pneumoniae via P116 to target liver and atherosclerotic lesions

14:15

Sabine Pereyre

32 - Eucaryotic cells trigger both ICE transfer and mosaic genome formation in Mycoplasma hominis

14:30

Birgit Henrich

79 - Activity of the M. hominis mobilome in infection and under therapy

14:45

Li Xiao

96 - In vitro evolution of Tetracycline resistance in Mycoplasma genitalium

15:00

Guoqing Shao

113 - AI-guided de novo design of antimicrobial peptides with dual mechanism for combating macrolide-resistant Mycoplasma pneumoniae and biofilms

15:15

Kavita Shrestha

128 - Regulation of Mycoplasma pneumoniae gene expression and virulence-associated proteins by oxygen

15:30

Elyse M. Levenda

148 - Urethral host cell damage caused by Mycoplasma penetrans and Mycoplasma genitalium

15:45-16:30

Short Talks 2

Chairs: Arlind Mara & Calvin Ko

Marco Bottinelli

81 - Temporal and tissue-specific patterns of mycoplasma isolation in dairy and meat cattle production systems: toward enhanced diagnostic appropriateness.

Anneke Feberwee

60 - The effect of windbreak mesh on Mycoplasma gallisepticum and Mycoplasma synoviae airborne transmission under in vitro conditions

Atsuko Nishino

94 - Integrated multi-omics analysis reveals a ph-driven metabolic and translational switch in Ureaplasma parvum

Harley Henderson

103 - Microbial profiling of Mycoplasma bovis associated with polymicrobial infections in feedlot cattle mortalities

Quoqing Shao

117 - AI for Mycoplasma: Development of four applicable tools

Maxime BOUTTIER

127 - New structural insights on Spiroplasma platyhelix cytoskeleton using CryoEM

Sneha Verma

138 - Characterization of TENGU effector homolog interactions in ‘Ca. Phytoplasma asteris’ implicated in the pathogenesis of sandal spike disease

Prescott Atkinson

161 - Disulfiram exhibits potent copper-dependent antimicrobial activity against Mycoplasma genitalium

16:30-17:00

Coffee Break

17:00-18:00

IRPCM meetings (Simultaneous)

Chemotherapy of mycoplasmas

Porcine Mycoplasmas

Molecular Genetics and Cell Biology

9:00

Keynote Lecture

Chair: Inna Lysnyansky

Yifat Merbl

‘Proteosome-derived defense peptides: what's next?’

9:50-13:00

Seminar 3 – Plant and Insect Mollicutes

Chairs: Kenro Oshima & Anna Sawicka - Durkalec

10:00

Chih-Horng Kuo

56 - Evaluating genome similarity metrics for species delineation in Mycoplasma and Ureaplasma

10:15

Martina Seruga Music

98 - Transcriptomic reprogramming of Arabidopsis thaliana seedlings by 'Candidatus Phytoplasma solani' SAP-like effectors

10:30-11:00

Coffee Break

11:00

Robert F. Whitecomb Award Lecture

Gail Gasparich

‘Spiroplasmas, Entomoplasmas and Mesoplasmas-Taxonomy and Phylogeny Past and Present’

11:50

Pratima Verma

23 - Diversity, effector distribution and evolutionary dynamics of phytoplasma infecting Sesamum indicum L. (sesame) across India.

12:04

Nian-Pu,Li

30 - Investigation of genomic diversity and branch-inducing mechanism of poinsettia branch-induced (poibi) phytoplasmas

12:18

Yumiko Masukagami

106 - Two convergently reduced clades of mollicutes of marine invertebrates retain extensive sets of defense mechanisms against viruses

12:32

Valeria Trivellone

132 - Global eco-evolutionary dynamics of Hemiptera-phytoplasma associations

12:46

Amit Yadav

156 - ‘Candidatus Phytoplasma yerunii’, a novel Elm Yellows lineage from Western India

13:00-14:00

Lunch Break

14:00 – 16:30

Symposium 3 – Virulence and Pathogenesis of Animal Mycoplasmas

Chairs: Chih-Horng Kuo & Rachel Derscheid

14:00

Gang Zhao

12 - Mycoplasma bovis infection reprograms extracellular vesicles derived from bovine mammary epithelial cells to amplify macrophage inflammatory responses

14:15

Aizhen Guo

17 - MbovP486 dna glycosylase protects Mycoplasma bovis from oxidative dna damage and enhances its survival

14:30

Rohini Chopra-Dewasthaly

61 - First evaluation of FTIR spectral profiling to monitor in vivo adaptation of Mycoplasma agalactiae: association with Vpma lipoprotein variation

14:45

Hasitha Himali Disanayaka Disanayaka Mudiyanselage

63 - In vitro coinfection dynamics of Mycoplasma gallisepticum and infectious laryngotracheitis virus

15:00

Zhenzhen Zhang

64 - A TNF-α–extracellular vesicle axis drives alveolar injury in Mycoplasma hyopneumoniae pneumonia

15:15

Claire A.M. Becker

67 - Diagnostic practices and use of antibiotics against mycoplasmoses in animal production: results of an international survey of veterinarians

15:30

Glenn Browning

50 - Effect of herd infection with Mycoplasma bovis on milk quality

15:45

Inna Lysnyansky

74 - In Praise of Doubt: Does the pathogenesis of Mycoplasma bovis mastitis deserve re-examination?

16:00

Veronica Jarocki

133 - Antimicrobial susceptibility and genomic analysis of Mycoplasma bovis isolated from bovine respiratory disease cases in Australian beef feedlots

16:15

Janina Kramer

146 - Evidence of strong host-dependency in the compact genome of ꞌCandidatus Mycoplasma haemosuisꞌ

16:30-17:00

Coffee Break

17:00:18:00

Poster Session 2 (Even number Abstracts)

18:00-19:00

IRPCM Meetings (Simultaneous)

Plant and Arthropod Mollicutes

Ruminant mycoplasmas

Comparative Immunology

9:00 – 12:00

Seminar 4 – Vaccines, Immunology and Infection models

Chairs: Elise Schieck & Steven Geary

9:00

Derrick Edward Award Lecture

Nadeeka Wawegama

“From bench to herd: diagnostic assay development and validation for Mycoplasma bovis control”

9.45

Miklós Gyuranecz

20 - Development and evaluation of an attenuated temperature-sensitive Mycoplasma hyorhinis vaccine candidate

10:00

Yonathan Arfi

35 - Characterizing the antibody response against Mycoplasma bovis at the epitope level with BoviScan, a Phage ImmunoPrecipitation Sequencing library

10:15

Maverick Monié—Ibanes

163 - Antibiotic-driven dysbiosis modulates Mycoplasmatales and BRDC disease severity in calves

10:30-11:00

Coffee Break

11:00

Ana Fiorella Castillo Espinoza

92 - Modeling host interactions with non-pathogenic and commensal swine Mycoplasma in a 3D Organotypic tracheal model

11:15

Arlind Mara

105 - Mouse models of ruminant respiratory mycoplasmoses

11:30

Beatriz Almeida Sampaio

131 - A recombinant Mycoplasma agalactiae subunit vaccine induces long-lasting immunity, bacterial clearance and distinct transcriptomic signatures in goats

11:45

Paola Vaz

157 - Investigations into viral-bacterial coinfections in respiratory diseases of animals across 2D, 3D and in vivo models.

12:00

Closing Ceremony

13:00

Lunch